유혜연1,손연정*2

아주대학교 의과대학 생리학교실1, 순천향대학교 간호학과2

Background: Elevated high sensitivity C-reactive protein (hs-CRP) and metabolic syndrome are well-known
predictors of coronary atherosclerosis. However, few data are available on the roles of hs-CRP and metabolic
syndrome on recurrent cardiac events in patients having undergone percutaneous coronary intervention (PCI).
This retrospective study examined the effects of pre-procedural hs-CRP and metabolic syndrome on recurrent
cardiac events in patients who underwent successful PCI.
Methods: This study included one hundred patients (with recurrence group=35, without recurrence group=65)
in their twenties to eighties admitted to a university hospital. Data were collected by a questionnaire and medical
records using convenience sampling.
Results: Pre-procedural hs-CRP levels were higher in the ‘with recurrence’ group than in the ‘without recurrence’ group (P=0.002). Prevalence of metabolic syndrome was not significant in the recurrence of cardiac
events. Logistic regression analysis was performed to delineate the factors affecting recurrent cardiac events
and showed that pre-procedural hs-CRP (P=0.002) was the only statistically significant parameter for the recurrence of cardiac events. In terms of risk for recurrent cardiac events, pre-procedural hs-CRP level of ‘above
3 mg/L’ was higher than that of ‘below 3 mg/L’ by 9.27 fold.
Conclusion: Our study showed that pre-procedural hs-CRP may predict recurrent cardiac events after successful PCI. Prospective studies conducted on larger populations would be needed to strengthen our findings.
Korean J Health Promot 2010;10(1):31-38

Key Words: PTCA, stents, coronary restenosis, C-reactive protein, metabolic syndrome