박혜영, 김진리, 서주영, 신경숙, 유병욱, 조용진, 오정은

순천향대학교 의과대학 순천향대학병원 가정의학과

Background: Recently, the prevalence of colorectal cancer related with metabolic syndrome is increasing in
Korea. The aim of this study was to reveal a relationship between components of metabolic syndrome and the
development of colon polyp.
Methods: Among the subjects who visited a health promotion center of one university hospital and underwent
colonoscopic examination from February 2010 to February 2011, a total of 1,630 (males 1,156, females 474)
asymptomatic adults were included for the study. Sex, age, body mass index, waist circumference, blood pressure,
fasting blood glucose, total cholesterol, triglyceride, HDL-cholesterol levels and the presence of colorectal
polyps were measured. Alcohol consumption, smoking and exercise were assessed by a self-administered
questionnaire. Metabolic syndrome was defined by criteria of 2004 American Heart Association/Updated NCEP
Adult Treatment Panel III.
Results:The prevalence of colon polyps and metabolic syndrome was 21.7% and 16.0% respectively among study subjects. After adjustment for sex and age, metabolic syndrome (odds ratio [OR]=1.72, 95% confidence
interval [CI] 1.05-2.82, P=0.031) and waist circumference (OR=1.04, 95% CI 1.01-1.06, P=0.009) were associated
with increased risk of colorectal polyps.

Conclusion: Metabolic syndrome and waist circumference were associated with increased risk of colon polyps in asymptomatic Korean adults.

Korean J Health Promot 2013;13(3):87-92

Keywords: Colon polyp, Metabolic syndrome, Waist circumference