전예림1, 정소현1, 강서영1, 김영식1, 전태희2, 이상엽3, 양윤준4, 김선미5, 윤종률6

1울산대학교 의과대학 서울아산병원 가정의학과, 2보훈공단 중앙보훈병원 가정의학과, 3부산대학교 의과대학 양산부산대학교병원 가정의학과, 4인제대학교 일산백병원 가정의학과, 5고려대학교 의과대학 고려대학교구로병원 가정의학과, 6한림대학교 의과대학 동탄성심병원 가정의학과

Background: The prevalence of hypertension reaches 29% in
adults over 30 years of age in the Korean population;
however, the control rate is merely 44%. The aim of this
study was to investigate the associated factors for target
blood pressure achievement after triple combination therapy
in hypertensive patients. Methods: From February 2016 to
May 2018, 10 family physicians recruited 348 patients, who
newly started a triple combination antihypertensive
medication. Target blood pressure was defined as a systolic
blood pressure (SBP) <140 mmHg and diastolic blood
pressure (DBP) <90 mmHg after 6 months of triple
combination therapy. Multivariate logistic regression
analyses were performed to analyze the associated factors
for target blood pressure achievement. Results: Among the
348 study participants, 317 completed 6 months of
treatment. The target achievement rate was 76.3%
(242/317). The mean absolute difference and 95%
confidence interval (CI) for the SBP and DBP were 10.8
mmHg (8.8 to 12.7) and 6.4 mmHg (5.1 to 7.8),
respectively (P<0.05). The odds ratio (OR) for the target
blood pressure achievement increased in those with college
education or higher (OR, 2.69; 95% CI, 1.22-5.92), those
with dyslipidemia (OR, 1.74; 95% CI, 1.01-2.99), and those
who were satisfied with the medication (OR, 29.91; 95% CI,
3.70-241.92). Conclusions: The presence of dyslipidemia
and patient’s satisfaction with the medication were
associated with target blood pressure achievement in our
analyses. Our findings suggest the importance of patient’s
factor in the control of blood pressure. Korean J Health
Promot 2019;19(1):16-24 Keywords: Hypertension,
Combination drug therapy, Control, Blood pressure