In Kyung Jun

Department of Beauty Art, Honam University, Gwangju, Korea


Background: Patients with metabolic syndrome had low high-density lipoprotein cholesterol (HDL-C) levels. Moreover, vitamin D deficiency is also related to metabolic syndrome. This study aimed to investigate the asso- ciation between vitamin D and HDL-C levels.
Methods: To determine the association between HDL-C and vitamin D levels, 5,537 males who had no missing values were systematically selected from the fifth Korea National Health and Nutrition Examination Survey. Then, the association was investigated by a multivariable logistic regression analysis after adjusting for the ef- fects of confounding factors on vitamin D and HDL-C levels, such as age, body mass index (BMI), sociodemo- graphic factors, and lifestyle factors.
Results: In Korean men aged ≥ 20 years, the mean vitamin D and HDL-C levels were 18.3±0.2 ng/mL and 46.8±0.2 mg/dL, respectively. Moreover, the prevalence of low HDL-C levels was 29.2±0.8%. After adjusting for age, BMI, sociodemographic factors, and lifestyle factors, the risk of low HDL-C levels in the lowest quartile of vitamin D level was 1.296 (95% confidence interval [CI], 1.035-1.623) times higher and that in the second quar- tile of vitamin D level was 1.354 (95% CI, 1.086-1.690) times higher than that in the third quartile of vitamin D level (P<0.05).
Conclusions: The risk of low HDL-C levels is associated with vitamin D level after adjustment for age, BMI, soci- odemographic factors, and lifestyle factors.
Korean J Health Promot 2019;19(4):210-220

Keywords: Vitamin D, HDL-cholesterol, Metabolic syndrome, Life style