Hei Young Park, Jin Ri Kim, Ju Young Seo, Kyung Suk Shin, Byung Wook Yoo, Yong Jin Cho, Jung Eun Oh

Department of Family Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea


Background: Recently, the prevalence of colorectal cancer related with metabolic syndrome is increasing in Korea. The aim of this study was to reveal a relationship between components of metabolic syndrome and the development of colon polyp.
Methods: Among the subjects who visited a health promotion center of one university hospital and underwent colonoscopic examination from February 2010 to February 2011, a total of 1,630 (males 1,156, females 474) asymptomatic adults were included for the study. Sex, age, body mass index, waist circumference, blood pressure, fasting blood glucose, total cholesterol, triglyceride, HDL-cholesterol levels and the presence of colorectal polyps were measured. Alcohol consumption, smoking and exercise were assessed by a self-administered questionnaire. Metabolic syndrome was defined by criteria of 2004 American Heart Association/Updated NCEP Adult Treatment Panel III.
Results:The prevalence of colon polyps and metabolic syndrome was 21.7% and 16.0% respectively among study subjects. After adjustment for sex and age, metabolic syndrome (odds ratio [OR]=1.72, 95% confidence interval [CI] 1.05-2.82, P=0.031) and waist circumference (OR=1.04, 95% CI 1.01-1.06, P=0.009) were associated with increased risk of colorectal polyps.
Conclusion: Metabolic syndrome and waist circumference were associated with increased risk of colon polyps in asymptomatic Korean adults.

Korean J Health Promot 2013;13(3):87-92

Keywords: Colon polyp, Metabolic syndrome, Waist circumference